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Investigator Ganesh Krishna, M.D.

Ganesh Krishna, M.D.

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Ganesh Krishna, M.D., is an Interventional Pulmonologist at Palo Alto Medical Foundation's Mountain View campus. His professional interests in critical care medicine include asthma, chronic obstructive pulmonary disease, cystic fibrosis, interstitial lung disease, lung disease, pulmonary fibrosis, and pulmonary hypertension. 

His interests in pulmonary disease include asbestos disease, cystic fibrosis, interstitial fibrosis, pulmonary fibrosis, and sarcoidosis

Dr. Krishna completed his medical training at Tirunelveli Medical College Hospital in Tirunelveli, India in 1990. He did his residency at George Washington University in Washington, DC.


Sutter Health Research Enterprise
701 E. El Camino Real
Mountain View, CA, 94040
(650) 934-7144  
krishng1@sutterhealth.org

Primary Research Interests

  • Autoimmune Disease
  • Bronchoscopic Procedures
  • COPD
  • Cancer
  • Disease Management
  • Environmental Exposure
  • HIV/AIDS
  • Infectious Disease
  • Lung Cancer
  • Lung Diseases
  • Lung Nodules Diagnostics

Related Clinical Trials

Liberate

Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study) (LIBERATE)

Investigator: Ganesh Krishna M.D.

Status: Active, Recruiting

RENEW Clinical Trial

Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study

Investigator: Ganesh Krishna M.D.

Publications

Using a dedicated interventional pulmonology practice decreases wait time before treatment initiation for new lung cancer diagnoses.

Obtaining a tissue bx dx through a gatekeeper interventional pulmonology practice decreases median delay from abnormal imaging to treatment initiation.

A multicenter RCT of Zephyr® Endobronchial Valve treatment in heterogeneous emphysema (LIBERATE).

Zephyr Endobronchial Valve provides clinically meaningful benefits in lung function, exercise tolerance, dyspnea and quality of life out to at least 12-months.

Improved targeting accuracy of lung tumor biopsies with scanning-beam digital x-ray tomosynthesis image guidance.

The SBDX system permits visualization of small lung nodules, as well as accurate measurement of channel-to-target distances. Combined use of ENB with SBDX real-time image guidance could improve accuracy and yield of biopsies, particularly of those lesions located in the periphery of the lung.

Effect of endobronchial coils vs usual care on exercise tolerance in patients with severe emphysema: the RENEW randomized clinical trial.

In pts with severe emphysema, endobronchial coils resulted in modest exercise tolerance and more likely major complications.

Electromagnetic navigational bronchoscopy spares a drunken crab from the surgeon's knife.

Used ENB to dx pulm infection, sparing pt unnec thoracotomy with lobectomy.

Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure.

Expert statement proposed during the third international conference on "Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease" (Ravenna, 10/27-28/2016).

Nivolumab-induced granulomatous inflammation of the pleura.

Article describes nivolumab-induced granulomatous inflammation of the pleura.

Endobronchial ultrasound-guided transbronchial needle injection of liposomal amphotericin B for the treatment of symptomatic aspergilloma.

This is the first reported tx of aspergilloma (in 71 yo female) with EBUS-guided transbronchial needle injection of liposomal amphotericin B.

Disseminated tuberculosis and lung cancer associated with infliximab treatment of rheumatoid arthritis.

Case of disseminated tuberculosis, possible infection with Mycobacterium fortuitum, and lung cancer in association with infliximab tx for rheumatoid arthritis.

Update on the treatment of lymphangioleiomyomatosis.

We describe the clinical, physiologic, radiologic, and pathologic characteristics of lymphangioleiomyomatosis, and discuss current and possible treatments.

The diagnostic yield of navigational bronchoscopy performed with propofol deep sedation.

The diagnostic yield of ENB utilizing propofol for procedural deep sedation at our center was excellent. ENB with deep sedation may result in superior diagnostic yield compared with ENB performed with moderate sedation.

A 24-year-old woman with bilateral pulmonary infiltrates, pericardial effusion, and bilateral pleural effusions.

1. RA flares may present with multiorgan involvement without exacerbation of articular symptoms.2. Bilateral, patchy, alveolar pulmonary infiltrates on chest

A 35-year-old man with fever, dyspnea, and diffuse reticular opacities.

NSIP should be considered in the differential diagnosis of a patient presenting with the subacute onset of fever, dyspnea, cough, & diffuse reticular opacities.

PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis.

The efficacy of PG490-88 when administered late after bleomycin installation suggests a potential role in the treatment of idiopathic pulmonary fibrosis.

Nodular invasive tracheobronchitis due to Aspergillus in a patient with systemic lupus erythematosus.

This is only the second report of fulminant invasive tracheobronchitis due to Aspergillus in a patient with an autoimmune disease.

The dying thoracic patient.

A nonconfrontational, sympathetic, and compassionate approach to family members and legal surrogates facing the immediate death of their loved ones leads to the best possible outcome.

Osseous Kaposi sarcoma.

Case of AIDS-associated Kaposi sarcoma with osseous involvement w/o any evidence of adjacent nonosseous lesions, suggesting metastatic dissemination.

Pneumonic plague.

Focus: prevalence, pathogenesis immunity, clinical manifestations, diagnosis, treatment, prevention of plague pneumonia, with emphasis on biologic warfare.

New therapies for chronic obstructive pulmonary disease.

We discuss novel therapeutic options and future research directions that may have an impact on COPD mgmt.

Parasitic pulmonary eosinophilia.

This review focuses on common and some uncommon causes of pulmonary parasitic eosinophilia and their manifestations, diagnosis, and management.

Advances in the management of chronic obstructive pulmonary disease.

COPD mgmt should involve a multi-pronged approach: smoking cessation, bronchodilators, infection tx, target inflammatory pathways/genetic predispositions.

Differential expression of monocyte/macrophage-selective markers in human idiopathic pulmonary fibrosis.

Observations reveal significant differences in cell/molecular markers involved in monocyte/macrophage activation and migration in idiopathic pulmonary fibrosis.

Smoking cessation therapy with varenicline.

Its targeted mechanism of action, better efficacy and tolerability makes varenicline a useful therapeutic option for smoking cessation.

Minimally invasive techniques for the diagnosis of peripheral pulmonary nodules.

Transthoracic biopsy may be particularly helpful when an infectious cause is suspected, pt is a marginal candidate for surgery, or malignancy proof is desired.

Transbronchial cryobiopsy: a new tool for lung biopsies.

Transbronchial cryobiopsy is a novel technique which allows to obtain large biopsy samples of lung parenchyma that exceed the size and quality of forceps biopsy samples.

Patient dose simulations for scanning-beam digital x-ray tomosynthesis of the lungs.

SBDX offers significant dose advantage over currently used C-arm fluoroscopy. Pt location with lowest dose coincides with the location of max tomographic angle.

Research Studies

Lung Function Improvement After Bronchoscopic Lung Volume Reduction With Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE)

This study investigates the safety and effectiveness of the Pulmonx EBV for treating emphysema symptoms as compared to a standard medical therapy alone.

Investigator: Ganesh Krishna M.D.

Safety and Effectiveness of the Spiration Valve System in Air Leaks (VAST)

Study will examine safety and efficacy of the Spiration Valve System in treating patients with prolonged air leaks compared to std. med. mgmt.

Investigator: Ganesh Krishna M.D.

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