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About the Diabetes Research Institute

The Dorothy L. and James E. Frank Diabetes Research Institute was created in 2000 to conduct clinical trials of devices and drugs with the goal of accelerating the development of products for people with diabetes. Dorothy and her husband James endowed the institute at Mills-Peninsula and were also contributors to many other organizations focused on diabetes research.

DRI is located at Mills-Peninsula Medical Center’s San Mateo Campus. The medical director and founder is David C. Klonoff, M.D., FACP, FRCP (Edin), Fellow AIMBE, a board-certified endocrinologist and Clinical Professor of Medicine at the University of California, San Francisco. 

The DRI has conducted over 110 clinical trials of diabetes drugs and devices. Studies have included the first commercial artificial pancreas system, the first dedicated diabetes digital health product, the first insulin patch pump and many types of insulins and other drugs for diabetes.

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