Electromagnetic navigational bronchoscopy spares a drunken crab from the surgeon's knife.
Abstract
Surgical resection is traditionally the preferred treatment for fluorodeoxyglucose-avid peripheral pulmonary nodules that grow over time.
However, new technologies, including electromagnetic navigational bronchoscopy (ENB), provide an opportunity to confirm or possibly exclude a cytologic cancer diagnosis, before resection.
We present a case of a 56-year-old North American man who presented with a fluorodeoxyglucose-avid pulmonary nodule and sought a second opinion after being recommended thoracotomy with lobectomy. The peripheral nodule was biopsied using ENB and pathologic evaluation of the lesion demonstrated parasitic eggs with features of Paragonimus westermani. No evidence of malignancy was found. The radiographic abnormalities resolved after treatment with praziquantel.
Using a minimally invasive procedure with ENB, we successfully diagnosed pulmonary infection with P. westermani, a rare infectious cause of peripheral pulmonary lesions in a patient without travel to an endemic area. Furthermore, an alternative diagnosis to cancer was established, sparing this patient an unnecessary thoracotomy with right middle lobectomy.
Research topics
Related publications
View all publications- Publication
Parasitic pulmonary eosinophilia.
Chitkara RK, Krishna G.Semin Respir Crit Care Med. 27(2):171-84.2006 Apr 01 - Katikireddy CK, Krishna G, Berry G, Faul J, Kuschner W.Chest. 128(6):4013-7.2005 Dec 01
- Sciurba FC, Criner GJ, Strange C, Shah PL, Michaud G, Connolly TA, Deslée G, Tillis WP, Delage A, Marquette CH, Krishna G, Kalhan R, Ferguson JS, Jantz M, Maldonado F, McKenna R, Majid A, Rai N, Gay S, Dransfield MT, Angel L, Maxfield R, Herth FJ, Wahidi MM, Mehta A, Slebos DJ; RENEW Study Research Group.JAMA. 315(20):2178-2189. doi: 10.1001/jama.2016.6261.2016 May 24
- Parikh MS, Seeley E, Nguyen-Tran E, Krishna G.J Bronchology Interv Pulmonol. doi: 10.1097/LBR.0000000000000383. [Epub ahead of print]2017 Jun 05
- Hetzel J, Maldonado F, Ravaglia C, Wells AU, Colby TV, Tomassetti S, Ryu JH, Fruchter O, Piciucchi S, Dubini A, Cavazza A, Chilosi M, Sverzellati N, Valeyre D, Leduc D, Walsh SLF, Gasparini S, Hetzel M, Hagmeyer L, Haentschel M, Eberhardt R, Darwiche K, Yarmus LB, Torrego A, Krishna G, Shah PL, Annema JT, Herth FJF, Poletti V.Respiration. doi: 10.1159/000484055. [Epub ahead of print]2018 Jan 09




