In this case - numbness of the 1st(thumb), 2nd and/ or 3rd digit of the hand is very classic for carpal tunnel syndrome. This condition is due to compression (entrapment) of a nerve that supplies the hand - called the median nerve. In many cases this can be treated with a wrist brace and anti-inflammatory medications. It can also help to modify certain activities at work or home, such as repetitive activities like gripping. In some cases where these steps don't help, an injection of cortisone into the wrist, or surgery of the wrist, can provide relief.
I would suggest seeing your family doctor, who can evaluate the condition and prescribe the best treatment.