Working with fellow CPMCRI researchers Drs. Pierre Desprez and Sean McAllister, Dr. Soroceanu is studying the inhibition and down-regulation of the protein Id-1 in brain tumor cells by cannabinoid compounds including cannabidiol (CBD). She is also determining the efficacy of CBD and related compounds in sensitizing tumors to frontline therapeutics (e.g., chemotherapy). With researchers in the Kashani lab at CPMCRI, Dr. Soroceanu is investigating the mechanisms by which PHIP enhances the aggressiveness of cancer and determining whether inhibiting the protein will alter the aggressive behaviors of gliomas in vivo.
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