The use of clinical characteristics to help prevent morcellation of leiomyosarcoma: An analysis of 491 cases.

Chan JK, Gardner AB, Thompson CA, Kapp DS., Am J Obstet Gynecol. 213(6):873-4. doi: 10.1016/j.ajog.2015.07.040. Epub 2015 Jul 29., 2015 Dec 01

Abstract

Minimally invasive surgery results in shorter recovery and improved quality of life.

The removal of the uterus or fibroids using morcellators to fragment the specimen can potentially spread unsuspected malignancy and result in poor prognosis.

Uterine leiomyosarcomas (LMS) comprise only 3% of uterine malignancies, but have similar characteristics to uterine fibroids.

Serum biomarkers and radiologic diagnostic criteria to preoperatively identify LMS have not been widely adopted.

Factors related to increased risk of LMS in patients with presumed benign leiomyoma, including older age and black race, have not been well defined.

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