Endobronchial ultrasound-guided transbronchial needle injection of liposomal amphotericin B for the treatment of symptomatic aspergilloma.

Parikh MS, Seeley E, Nguyen-Tran E, Krishna G., J Bronchology Interv Pulmonol. doi: 10.1097/LBR.0000000000000383. [Epub ahead of print], 2017 Jun 05

Investigators

Ganesh Krishna, M.D.

Abstract

Surgical treatment with lung resection has traditionally been the treatment of choice for pulmonary cavities containing aspergillomas that cause hemoptysis.

Endobronchial ultrasound (EBUS) is a minimally invasive bronchoscopic technique that is commonly used for transbronchial needle aspiration of hilar and mediastinal lymph nodes as well as centrally located parenchymal lesions.

Here, we describe a case of a 71-year-old woman who was found to have a cavitary lesion in the lung containing aspergillomas. Under direct ultrasound visualization with EBUS, liposomal amphotericin B was injected into the   aspergillomas. These aspergillomas regressed after treatment.

To our knowledge, this is the first reported treatment of aspergilloma with EBUS-guided transbronchial needle injection of liposomal amphotericin B.

Pubmed Abstract

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