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PAMF Hepatitis C Care

Nearly 4 million people in the United States have chronic hepatitis C, yet many don’t know it. Liver specialists at Palo Alto Medical Foundation network offer effective new therapies to treat and manage hepatitis C.

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Connect with a Liver Specialist

Featured Services

  • Liver Transplant

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Hepatitis C Care within the Sutter Health network

The Sutter Health network has doctors and services in more than 100 California cities.

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    Hepatitis C Care

    Hepatitis C, known as "the silent epidemic" because many people have mild or no symptoms, can lead to cirrhosis and ultimately liver cancer. It’s the leading cause of liver transplant in the United States.

    Exciting advances have been made in the treatment of hepatitis C, and Sutter Health is in the vanguard in hepatitis C management, treatment and research. California Pacific’s Liver Disease Management and Transplant Center serves as a hub for viral hepatitis research, offering clinical trials of new antiviral agents.

    A blood-borne virus, hepatitis C risk factors include multiple blood transfusions prior to 1990 (the virus was identified in 1989), intravenous drug use, body tattoos and multiple sex partners. Persons who have served in the military, healthcare workers and women who had cesarean sections prior to 1990 have higher risks of infection.

    Screening

    Identifying carriers is a high priority for Medicare, which covers one hepatitis C screening for anyone:

    • Ages 18 to 79
    • Who had blood transfusions before 1992
    • At high risk for infection due to current or past intravenous drug use

    Medicare requires that your primary care doctor order the hepatitis virus panel. If antibodies are detected, you may be referred to a liver specialist, who will order further tests.

    Disease Management

    If you have chronic hepatitis C, a liver specialist can monitor the progress of your disease using liver function tests and, if necessary, liver biopsy to assess the extent of fibrosis, a precursor to cirrhosis. A noninvasive imaging exam called Fibroscan measures the stiffness of the liver and is another way to assess the extent of fibrosis.

    Therapy

    There are four stages of fibrosis. If you have stage 0 or 1 fibrosis, you have mild hepatitis C. If you have stage 3 or 4, you are at risk for developing cirrhosis. Specialists will work with you to discuss therapy with antiviral drugs to reduce the virus’s ability to reproduce.

    Current standard treatment combines medications called Pegylated interferon-alpha-2a or Pegylated interferon-alpha-2b (brand names Pegasys® or PEG-Intron®) and antiviral ribavirin, administered for 24 or 48 weeks.

    Doctors generally recommend treatment for people with proven hepatitis C virus infection, persistently abnormal liver function tests and a liver biopsy that shows significant fibrosis. Therapy clears the virus in 70 to 80 percent of those infected with HCV genotypes 2 and 3 and in about 45 percent of those infected with genotype 1.

    Only about 15 percent of hepatitis C-infected patients will go on to develop cirrhosis during their lifetime. The majority of people with hepatitis C will never need a liver transplant.

    In Your Corner

    Doctor checking on a patient at the ER

    Defending the Liver from Cirrhosis

    Many liver diseases, hepatitis C included, can cause cirrhosis, which negatively impacts your liver’s ability to perform its many functions. With an early diagnosis and management of your disease, liver specialists in the Sutter Health network can help you stop and sometimes reverse the damage.

    Liver Diseases and Transplant Research

    Sutter Health Liver Diseases and Transplant Research
    Hepatology researchers are investigating the cellular and molecular mechanisms underlying hepatitis B, C and other liver diseases. Identifying early molecular or genetic changes - which may be detected before the disease manifests any clinical symptoms - could lead to interventions that reduce the severity of liver disease, or even prevent it from developing. Clinical researchers in the Liver Disease Management and Transplant Program are leading new investigations into hepatitis B and C disease management, hepatoma, hepatitis and HIV co-infection, nonalcoholic steatohepatitis, hepatorenal syndrome, and the care of liver transplant patients.

    Sutter Health Liver Diseases and Transplant Research Sutter Health Liver Diseases and Transplant Research

    Services Near You

    Fremont Center

    Fremont Center

    3200 Kearney Street

    Fremont, CA 94538

    (510) 490-1222

    Burlingame Center

    Burlingame Center

    1501 Trousdale Drive

    Building B

    Burlingame, CA 94010

    Mountain View Center

    Mountain View Center

    701 East El Camino Real

    Mountain View, CA 94040

    (650) 934-7000

    Dublin Center

    Dublin Center

    4050 Dublin Blvd.

    Dublin, CA 94568-3112

    (925) 875-6100

    Santa Cruz Gastroenterology

    Santa Cruz Gastroenterology

    1662 Dominican Way

    Santa Cruz, CA 95065

    (831) 460-7350

    Palo Alto Center

    Palo Alto Center

    795 El Camino Real

    Palo Alto, CA 94301

    (650) 321-4121

    San Carlos Center

    San Carlos Center

    301 Industrial Road

    San Carlos, CA 94070

    (650) 321-4121

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